| Platinum | RESIDENT EVIL 6 Platinum Trophy | Congratulations! You've overcome all your fears in RESIDENT EVIL 6! | 1.7% Ultra Rare | 873 pts |
| Bronze | Sneaking Around | Get through the aircraft carrier's bridge area without being noticed. | 2.8% Ultra Rare | 162 pts |
| Gold | Leave It to the Pro | Complete the entire game on Professional. | 3% Ultra Rare | 310 pts |
| Gold | Mad Skillz | Max out all the skills that allow you to level up. | 3.2% Ultra Rare | 299 pts |
| Silver | Heirlooms | Collect all the serpent emblems. | 3.2% Ultra Rare | 224 pts |
| Silver | Weapons Master | Use all the weapons in the game and kill ten enemies with each of them. | 3.8% Ultra Rare | 202 pts |
| Silver | Back in My Day | Complete the entire game on Veteran. | 4% Ultra Rare | 196 pts |
| Bronze | High Voltage | Defeat ten enemies with a stun rod charge attack. | 4.2% Ultra Rare | 127 pts |
| Bronze | Bring the Heat | Take down an enemy from 50 meters away with a headshot using the thermal scope. | 5.6% Very Rare | 107 pts |
| Bronze | Hard Choice | Shoot the helicopter pilot with a Magnum at point-blank range. | 5.8% Very Rare | 104 pts |
| Bronze | Stuntman | Defeat 20 enemies with the Hydra using a quick shot. | 6% Very Rare | 102 pts |
| Silver | Covered in Brass | Earn 150 different medals. | 7.6% Very Rare | 133 pts |
| Bronze | Flying Ace | Pilot the VTOL without getting a scratch on it. | 8.1% Very Rare | 86 pts |
| Bronze | They're ACTION Figures! | Collect 3 figures. | 8.6% Very Rare | 82 pts |
| Silver | Normal Is Good | Complete the entire game on Normal. | 12.4% Rare | 99 pts |
| Silver | B.O.W.s Are Ugly | Defeat 100 enemies that have come out of a chrysalid. | 12.9% Rare | 97 pts |
| Bronze | Give a Little Push | Knock ten enemies off a high place. | 13.9% Rare | 62 pts |
| Bronze | Bob and Weave | Counter an enemy's attack three times in row. | 14.7% Rare | 60 pts |
| Bronze | I Prefer Them Alive | Rescue two female survivors at the cathedral. | 19.2% Rare | 51 pts |
| Bronze | Green around the Ears | Complete the entire game on Amateur. | 21.5% Uncommon | 48 pts |
| Bronze | What's Next? | Complete Chapter 5 in Ada's campaign. | 23.3% Uncommon | 45 pts |
| Bronze | Ada's Demise | Complete Chapter 4 in Ada's campaign. | 23.7% Uncommon | 45 pts |
| Bronze | This Takes Me Back | Complete Chapter 3 in Ada's campaign. | 24.6% Uncommon | 44 pts |
| Bronze | Counterintelligence | Complete Chapter 2 in Ada's campaign. | 25.5% Uncommon | 43 pts |
| Bronze | I Spy | Complete Chapter 1 in Ada's campaign. | 27.9% Uncommon | 41 pts |
| Bronze | See You Around | Complete Chapter 5 in Jake's campaign. | 30% Uncommon | 39 pts |
| Bronze | Still on the Run | Complete Chapter 4 in Jake's campaign. | 31% Uncommon | 38 pts |
| Silver | Rising Up | Earn a level-four title. | 31.2% Uncommon | 57 pts |
| Bronze | Duty Calls | Complete Chapter 5 in Chris' campaign. | 31.3% Uncommon | 38 pts |
| Bronze | J'avo Genocide | Defeat 500 J'avo. | 32% Uncommon | 38 pts |
| Bronze | Let's Blow This Joint | Complete Chapter 3 in Jake's campaign. | 32.4% Uncommon | 37 pts |
| Bronze | A Revolting Development | Complete Chapter 2 in Jake's campaign. | 33.6% Uncommon | 36 pts |
| Bronze | There's Always Hope | Complete Chapter 4 in Chris' campaign. | 34.4% Uncommon | 36 pts |
| Bronze | Check Out My Dogs | Customize your dog tags. | 35.9% Uncommon | 35 pts |
| Bronze | After Her! | Complete Chapter 3 in Chris' campaign. | 36% Uncommon | 35 pts |
| Bronze | Money Talks | Complete Chapter 1 in Jake's campaign. | 36.9% Uncommon | 34 pts |
| Bronze | Down, Not Out | Defeat an enemy while dying, then recover without any help. | 37.6% Uncommon | 34 pts |
| Bronze | Tragedy in Europe | Complete Chapter 2 in Chris' campaign. | 39.1% Uncommon | 33 pts |
| Bronze | Finish What You Start | Perform a coup de grâce on ten enemies. | 40.8% Common | 32 pts |
| Bronze | The Trouble with Women | Complete Chapter 5 in Leon's campaign. | 41.3% Common | 32 pts |
| Bronze | Rescue the Hostages | Complete Chapter 1 in Chris' campaign. | 44.4% Common | 31 pts |
| Bronze | Big Trouble in China | Complete Chapter 4 in Leon's campaign. | 44.4% Common | 31 pts |
| Bronze | Titular Achievement | Earn 10 different titles. | 44.5% Common | 31 pts |
| Bronze | Silent Killer | Use a stealth attack to take down five enemies. | 46.7% Common | 30 pts |
| Bronze | Get on the Plane | Complete Chapter 3 in Leon's campaign. | 46.8% Common | 30 pts |
| Bronze | Zombie Massacre | Defeat 500 zombies. | 47% Common | 30 pts |
| Bronze | Lifesaver | Help or rescue your partner ten times. | 48.6% Common | 29 pts |
| Bronze | Buried Secrets | Complete Chapter 2 in Leon's campaign. | 49.6% Common | 29 pts |
| Bronze | Gone to Hell | Complete Chapter 1 in Leon's campaign. | 56.6% Common | 27 pts |
| Bronze | One Is Better Than None | Purchase one skill. | 60.5% Common | 26 pts |
| Bronze | The Longest Night | Complete the tutorial. | 84% Common | 21 pts |