| Platinum | Devil May Cry | Unlock all trophies. | 0.3% Ultra Rare | 7,414 pts |
| Gold | Worthy of Legend | Clear all missions with S rank on all difficulties except Heaven or Hell.
| 0.4% Ultra Rare | 3,119 pts |
| Gold | Highway to Hell | Complete the game on Hell and Hell mode. | 0.5% Ultra Rare | 2,728 pts |
| Silver | Stairway to Heaven | Complete the game on Heaven or Hell mode. | 1.5% Ultra Rare | 1,058 pts |
| Bronze | Who Needs Weapons Anyway? | Clear Mission 11 without equipping a weapon set for Dante (any difficulty except Heaven or Hell).
| 1.6% Ultra Rare | 679 pts |
| Silver | Hell of a Hunter | Clear all missions with S rank.
| 1.9% Ultra Rare | 919 pts |
| Bronze | Be the Legend | Acquire all of Dante's skills.
| 2.3% Ultra Rare | 546 pts |
| Silver | Dance with the Devil | Complete the game on Dante Must Die mode. | 2.5% Ultra Rare | 779 pts |
| Bronze | Dante The Gambler | Use more than 500,000 Red Orbs total with Dr. Faust.
| 2.6% Ultra Rare | 507 pts |
| Bronze | Demon Breeder | Acquire all of V's skills.
| 3% Ultra Rare | 466 pts |
| Bronze | Nothing's Impossible | Acquire all of Nero's skills.
| 3.4% Ultra Rare | 432 pts |
| Silver | Secrets Exposed | Clear all secret missions.
| 3.8% Ultra Rare | 606 pts |
| Bronze | The Devil's Own | Upgrade your Devil Trigger Gauge to max.
| 3.8% Ultra Rare | 404 pts |
| Bronze | Physical Perfection | Upgrade your vitality gauge to max.
| 3.9% Ultra Rare | 398 pts |
| Bronze | Rearm and Repeat | Collect more than 100 Devil Breakers during missions.
| 4.9% Ultra Rare | 347 pts |
| Gold | Well I'll Be Damned | Wield overwhelming power to exact an unexpected conclusion. | 5.5% Very Rare | 647 pts |
| Bronze | Doing Daddy Proud | Complete the game on Son of Sparda mode. | 5.8% Very Rare | 313 pts |
| Bronze | Each In His Own Way | Clear Mission 13 with Nero, V, and Dante.
| 5.9% Very Rare | 310 pts |
| Bronze | Unarmed and Dangerous | Beat Mission 07 without any starting Devil Breakers equipped (any difficulty except Heaven or Hell). | 6.9% Very Rare | 282 pts |
| Bronze | Battle for the Ages | Clear Missions 19 and 20 without using continues (any difficulty except Heaven or Hell).
| 8.4% Very Rare | 251 pts |
| Bronze | The Quick and the Dead | Defeat 5 enemies in 1 second.
| 9.8% Very Rare | 229 pts |
| Bronze | Share the Pain | Clear Mission 07 with both Nero and V.
| 11% Rare | 214 pts |
| Bronze | Pet Protection | Clear Mission 05 without V's demons getting stalemated (any difficulty except Heaven or Hell).
| 11.1% Rare | 212 pts |
| Bronze | Slick Moves | Proceed with caution and avoid unneeded damage in Mission 15. | 16.3% Rare | 169 pts |
| Bronze | Where the Red Orbs Grow | Collected Red Orbs from an unexpected spot in Mission 02. | 16.8% Rare | 166 pts |
| Silver | Jackpot! | Collect more than 1,000,000 Red Orbs total.
| 17.3% Rare | 244 pts |
| Bronze | Demon Destroyer | Defeat 1,000 enemies total.
| 17.4% Rare | 162 pts |
| Bronze | Let's Rock! | Complete the game on Human mode. | 22.3% Uncommon | 140 pts |
| Bronze | Obedience Training | Go on the offensive without relying on brute force in the Mission 16 boss battle.
| 22.9% Uncommon | 138 pts |
| Bronze | Showtime! | Complete the game on Devil Hunter mode. | 23.3% Uncommon | 136 pts |
| Bronze | Eagle-Eyed | Destroy a certain wall in Mission 09. | 24.7% Uncommon | 131 pts |
| Bronze | A New Job | Accept a new job from Morrison after the Red Grave incident. | 33.8% Uncommon | 109 pts |
| Bronze | I Believe I Can Fly | Rack up a total of 60 minutes in the air by jumping or other means.
| 40.1% Common | 98 pts |
| Bronze | Backroad | Destroy a certain wall in Mission 04. | 40.4% Common | 98 pts |
| Bronze | Man on a Mission | Clear Mission 18.
| 42.3% Common | 95 pts |
| Bronze | Back to Life | Clear Mission 17.
| 42.9% Common | 94 pts |
| Bronze | Protect the People | Defeat all enemies in Mission 01. | 43.8% Common | 93 pts |
| Bronze | Gotta Hurry | Clear Mission 14.
| 45.2% Common | 91 pts |
| Bronze | The Qliphoth | Clear Mission 12.
| 47.4% Common | 89 pts |
| Bronze | Don't Mess with the Best | Use proper timing to get a leg up in a close-quarters battle against the boss in Mission 11. | 48.2% Common | 88 pts |
| Bronze | Seriously Stylish Slaying! | Perform a Stylish Rank SSS combo.
| 49.4% Common | 87 pts |
| Bronze | This Ain't Over | Clear Mission 10.
| 50.1% Common | 86 pts |
| Bronze | Break a Leg | Fend off a menace from above in Mission 05.
| 50.8% Common | 85 pts |
| Bronze | Light in the Darkness | Clear Mission 08.
| 52.6% Common | 83 pts |
| Bronze | End of the Line | Clear Mission 06.
| 56.1% Common | 80 pts |
| Bronze | Steppin' up the Style | Perform a Stylish Rank SS combo.
| 59.3% Common | 78 pts |
| Bronze | Reunion | Clear Mission 03.
| 62.6% Common | 75 pts |
| Bronze | Not Too Shabby | Perform a Stylish Rank S combo. | 68.2% Common | 71 pts |
| Bronze | Fall from Grace | Clear the Prologue Mission. | 85.6% Common | 62 pts |