| Platinum | Who Do You Voodoo? | Collect every Dead Island 2 trophy! | 3.1% Ultra Rare | 203 pts |
| Silver | Bucket List | Complete the first tier of every Combat Challenge. | 3.5% Ultra Rare | 71 pts |
| Bronze | Donk! | Throw a melee weapon and hit a zombie 35+ meters away. | 5.5% Very Rare | 36 pts |
| Silver | Survival Skills | Complete the first tier of every Survivor Challenge. | 5.6% Very Rare | 53 pts |
| Silver | Sole Survivor | Complete 9 Lost & Found Missing Person Quests. | 7.7% Very Rare | 44 pts |
| Silver | Sharpest Tool in the Box | Complete 5 Lost & Found Weapon Quests. | 7.8% Very Rare | 44 pts |
| Gold | LA Influential | Complete 40 non-Story Quests. | 8.6% Very Rare | 55 pts |
| Bronze | Gore Horse | Help an artist to complete their greatest (and grisliest) piece of art. | 8.9% Very Rare | 27 pts |
| Silver | On Safari | Complete the first tier of every Zombie Challenge. | 10.5% Rare | 37 pts |
| Bronze | Make it So | Help Sarah and Sebastian light a beacon of hope. | 10.7% Rare | 24 pts |
| Silver | Variety is the Spice of Death | Complete the first tier of every Weapon Challenge. | 11% Rare | 36 pts |
| Gold | Max Headroom | Reach level 30. | 11.3% Rare | 47 pts |
| Bronze | Not Even My Final Form | Slay a Mutator before it transforms. | 11.3% Rare | 23 pts |
| Bronze | Internet Famous | Complete Amanda's Clickbait quests. You won't believe what happens next! | 12.1% Rare | 22 pts |
| Silver | Smorgasbord | Complete the first tier of every Exploration Challenge. | 12.2% Rare | 33 pts |
| Silver | Jumbo Keyring | Unlock 10 Lockboxes | 13.8% Rare | 31 pts |
| Silver | Rising Star | Complete 20 non-Story Quests. | 15.3% Rare | 29 pts |
| Bronze | Go, Bobcats! | Reunite all the VCLA Bobcats. | 15.8% Rare | 19 pts |
| Bronze | I Am the Resurrection | Revive other Slayers 5 times. | 18.1% Rare | 18 pts |
| Bronze | Down with the Sickness | Reach the highest tier of Autophage infection by equipping Autophage Skills. | 18.2% Rare | 18 pts |
| Bronze | Slayer Squad | Complete any 5 quests in co-op. | 19.9% Rare | 17 pts |
| Bronze | Making Your Mark | Complete 10 non-Story Quests. | 21.3% Uncommon | 16 pts |
| Bronze | Ooh, Shiny! | Find your first Legendary Weapon. | 22.8% Uncommon | 15 pts |
| Gold | Our True Nature | Give up your chance to be human again. | 23.5% Uncommon | 30 pts |
| Bronze | Zombologist | Unlock every zombie type in the Zompedia. | 23.7% Uncommon | 15 pts |
| Bronze | Humanity Distilled | Equip your first Numen Skill Card. | 24.3% Uncommon | 15 pts |
| Bronze | A Patton Emerges | Survive the Metro system and get to Hollywood Boulevard. | 24.8% Uncommon | 15 pts |
| Bronze | Like Riding a Bike | Find Patton and convince him to fly you out of Hell-A. | 25.9% Uncommon | 14 pts |
| Bronze | Perks of the Job | Complete 5 Blueprint Challenges. | 26.1% Uncommon | 14 pts |
| Bronze | Can't Handle the Truth | Learn the truth about what you are as dark secrets are revealed. | 26.5% Uncommon | 14 pts |
| Bronze | Anger Management | Slay 50 zombies with Fury Attacks. | 28.3% Uncommon | 13 pts |
| Bronze | But Doctor, I Am Butcho | Slay a killer clown and get your blood sample back to Dr. Reed. | 28.3% Uncommon | 13 pts |
| Bronze | This is My Weapon | Fully upgrade a Superior weapon and customize it with a mod or perk in every slot. | 28.7% Uncommon | 13 pts |
| Bronze | Stacking the Deck | Collect 30 Skill Cards. | 31.2% Uncommon | 13 pts |
| Silver | Bookworm | Collect 50 Journals. | 32.1% Uncommon | 19 pts |
| Bronze | Dr. Reed, I Presume? | Survive the many perils of Venice Beach and meet Dr. Reed at the Serling Hotel. | 32.7% Uncommon | 12 pts |
| Bronze | I Got a Zombie Army and You Can't Harm Me | Perform 25 perfect defensive moves. | 35.1% Uncommon | 12 pts |
| Bronze | Friends Like These | Encounter a mysterious... benefactor? Well, that's what she'd call herself, anyway. | 35.6% Uncommon | 12 pts |
| Bronze | Apex Predator | Knock down 10 Apex Variants.
| 36.4% Uncommon | 12 pts |
| Bronze | Git Gutte! | Join forces with Sam B and get your hands on some firepower. | 38.6% Uncommon | 11 pts |
| Bronze | Personal Assistant Personally Assisted | Track down Michael and rescue him from the Terror at Monarch Studios. | 40.1% Common | 11 pts |
| Bronze | Hazardous Materials | Slay 100 Zombies using Caustic, Fire, or Shock damage. | 45% Common | 10 pts |
| Bronze | Coup de Grâce | Slay 25 zombies using finishing moves. | 47.3% Common | 10 pts |
| Bronze | Break a Leg | Maim 100 limbs. | 55.1% Common | 9 pts |
| Bronze | Hotel California | Fight through the Halperin Hotel to make contact with the authorities. | 57.4% Common | 9 pts |
| Bronze | Welcome To Hell-A | Survive a plane crash, get bitten, and create your first Zombie-Free Zone. | 72% Common | 8 pts |