| Platinum | Dedicated | Collect all Trophies | 13.7% Rare | 83 pts |
| Bronze | Soar | Using only your Web Wings, glide from the Financial District to Astoria (Wind Tunnels are okay!) | 15.3% Rare | 19 pts |
| Bronze | Just Let Go | As Miles, find the science trophy Miles and Phin won together | 16.3% Rare | 19 pts |
| Bronze | Home Run! | Round the bases at the Big Apple Ballers Stadium | 17.8% Rare | 18 pts |
| Bronze | You Know What to Do | As Peter, visit Aunt May's grave | 18% Rare | 18 pts |
| Silver | Surge | Use Symbiote Abilities 25 times during Symbiote Surge | 22% Uncommon | 23 pts |
| Bronze | Hang Ten | Perform 30 Air Tricks in a row without touching the ground | 22.1% Uncommon | 16 pts |
| Gold | Superior | 100% complete all districts | 22.5% Uncommon | 31 pts |
| Bronze | Funky Wireless Protocols | Solve the mystery of the Spider-Bots' origin | 23.6% Uncommon | 15 pts |
| Silver | Kitted Out | Purchase all available Suits | 23.9% Uncommon | 22 pts |
| Silver | Foundational | Complete all EMF Experiments | 27.7% Uncommon | 20 pts |
| Bronze | Fully Loaded | Purchase all of Spider-Man's Suit Tech upgrades | 28.5% Uncommon | 13 pts |
| Silver | To the Max | Purchase all Gadget upgrades | 29% Uncommon | 20 pts |
| Bronze | New York, New York | Complete all Photo Ops | 30.2% Uncommon | 13 pts |
| Bronze | Slack Line | Stealth takedown 25 enemies in stealth from the Web Line | 30.2% Uncommon | 13 pts |
| Silver | Behind the Masks | Complete "Grand Finale" | 30.3% Uncommon | 19 pts |
| Silver | Data Collector | Complete "Target Identified" | 30.5% Uncommon | 19 pts |
| Bronze | Co-Signing | Complete all Tech Stashes | 30.5% Uncommon | 13 pts |
| Silver | Friendly Neighborhood Spider-Man | Complete all FNSM requests | 31.6% Uncommon | 19 pts |
| Silver | Exterminator | Complete all Symbiote Nests | 33.4% Uncommon | 18 pts |
| Silver | Amazing | Reach max level | 33.5% Uncommon | 18 pts |
| Silver | Armed and Dangerous | Defeat 100 enemies with Spider Arm abilities | 34% Uncommon | 18 pts |
| Silver | Seek and Destroy | Complete all Hunter Bases | 34.4% Uncommon | 18 pts |
| Bronze | Brooklyn Pride | Complete "A Gift" | 34.4% Uncommon | 12 pts |
| Bronze | A New Adventure | Help Howard | 36.3% Uncommon | 12 pts |
| Silver | Grains of Sand | Piece together broken memories | 36.4% Uncommon | 17 pts |
| Bronze | Resourceful | Collect a total of 10,000 Tech Parts | 38% Uncommon | 11 pts |
| Silver | Crimson Hour | Complete "It Was Meant for Me" | 38.9% Uncommon | 17 pts |
| Silver | Evolved | Defeat 100 enemies with Evolved Venom abilities | 39.4% Uncommon | 17 pts |
| Bronze | My Community | Complete "Hard Bop" | 40.2% Common | 11 pts |
| Gold | Heal the World | Finish the main story | 49.4% Common | 19 pts |
| Bronze | Antidote | Defeat a Symbiote that is under the effect of Anti-Venom status | 52.1% Common | 9 pts |
| Bronze | I Quit | Complete "This Isn't You" | 52.5% Common | 9 pts |
| Silver | Leave Us Alone | Complete "Don't Be Scared" | 53.8% Common | 14 pts |
| Silver | The Great Hunt | Complete "Anything Can Be Broken" | 54.2% Common | 14 pts |
| Bronze | Overdrive | As Miles, use Reverse Flux to pull 6 or more enemies together simultaneously | 54.2% Common | 9 pts |
| Bronze | Splat | Attempt and fail a trick before "landing" on the ground | 54.8% Common | 9 pts |
| Bronze | Another Way | Complete "No Escape" | 55.1% Common | 9 pts |
| Silver | Medicine | Complete "It Chose You" | 56.7% Common | 13 pts |
| Bronze | A New Suit | Acquire the Black Suit | 60.5% Common | 9 pts |
| Bronze | Stylish | Equip a suit style | 73.1% Common | 8 pts |
| Bronze | You're Gonna Need Help | Complete "Surface Tension" | 87.4% Common | 7 pts |