| Platinum | Brave New World | Obtain all trophies. | 1.1% Ultra Rare | 1,133 pts |
| Gold | Aren't You Thankful? | Complete the game on Hardcore Mode. | 1.4% Ultra Rare | 490 pts |
| Bronze | Axes High | Kill 30 enemies using Fodder axes. | 1.5% Ultra Rare | 235 pts |
| Bronze | Drill Sergeant | Complete the Drill Room without taking any damage. | 1.6% Ultra Rare | 226 pts |
| Silver | Survivalist | Complete the game in Pure Survival Mode. | 1.9% Ultra Rare | 306 pts |
| Bronze | The Professor | Collect all Artifacts. | 2.1% Ultra Rare | 192 pts |
| Bronze | Gun Collector | Collect all Weapon Parts. | 2.1% Ultra Rare | 192 pts |
| Bronze | The Armorer | Collect all Circuits. | 2.1% Ultra Rare | 192 pts |
| Silver | Epic Tier 4 Engineer | Complete the game in Classic Mode. | 2.6% Ultra Rare | 254 pts |
| Silver | Weedkiller | Kill 5 Cysts in the Biology Building with a single poison gas cloud. | 2.6% Ultra Rare | 254 pts |
| Bronze | The Librarian | Collect all Logs. | 2.6% Ultra Rare | 169 pts |
| Bronze | Aliens | Collect all Alien Artifacts. | 3.1% Ultra Rare | 152 pts |
| Bronze | The Explorer | Complete all optional missions. | 4.3% Ultra Rare | 125 pts |
| Silver | There's Always Peng! | Find Peng. | 4.6% Ultra Rare | 180 pts |
| Bronze | Electric Lawnmower | Kill 30 enemies using an electrified Ripper blade. | 4.9% Ultra Rare | 116 pts |
| Silver | Ghosts of the Past | Face all of Carver’s demons by completing all Co-Op only optional missions. | 5% Very Rare | 171 pts |
| Bronze | Hungry | Reach the pump room of the Waystation without alerting any Feeders. | 5.1% Very Rare | 113 pts |
| Bronze | Medic! | Revive your Co-Op partner 10 times. | 5.2% Very Rare | 112 pts |
| Bronze | Architect | Share a Blueprint with your Co-Op partner. | 5.8% Very Rare | 104 pts |
| Bronze | And Then We Doubled It! | Dismember 1000 limbs from living enemies. | 7.9% Very Rare | 87 pts |
| Bronze | Payback | Kill a Soldier by TK'ing a grenade or rocket back at them. | 10.8% Rare | 72 pts |
| Bronze | Shootbang | Kill 30 Soldiers with head shots. | 11.5% Rare | 69 pts |
| Bronze | Under a Buck | Shoot the deer head trophy in the Admiral's Quarters. | 11.7% Rare | 69 pts |
| Bronze | Dropping Acid | Dissolve 50 enemies with acid. | 11.9% Rare | 68 pts |
| Bronze | Space Ace | Shoot at least 70 targets during the ride to Tau Volantis. | 12.2% Rare | 67 pts |
| Bronze | From the Jaws | Save your Co-Op partner from an execution by killing the attacker. | 14.2% Rare | 61 pts |
| Bronze | Share and Share Alike | Use the RIG to give an item to your Co-Op partner. | 15.2% Rare | 59 pts |
| Silver | RIG Master | Fully upgrade your RIG. | 15.5% Rare | 87 pts |
| Bronze | Blast Corps | Kill 30 enemies with explosion damage. | 16% Rare | 57 pts |
| Bronze | Metal Detector | Successfully deploy Scavenger Bots to 15 Resource Areas. | 16.6% Rare | 56 pts |
| Bronze | Empty Chamber | Kill 30 enemies using melee strikes or a melee Weapon Part. | 21.7% Uncommon | 47 pts |
| Bronze | Master Plan | Create a Blueprint that needs at least 2000 resources worth of parts and Circuits to build. | 22.4% Uncommon | 46 pts |
| Bronze | Close Encounter | Kill 10 alien Necromorphs. | 23.1% Uncommon | 46 pts |
| Bronze | Slow Mo | Kill 50 enemies while they are in stasis. | 24.6% Uncommon | 44 pts |
| Bronze | Go for the Limbs! | Dismember 500 limbs from living enemies. | 25.1% Uncommon | 43 pts |
| Bronze | Get On My Level | Complete the game on any difficulty setting. | 26.5% Uncommon | 42 pts |
| Gold | Shoot for the Moon | Defeat the Moon. | 27% Uncommon | 83 pts |
| Bronze | Infernal Machine | Reach the Alien Machine. | 28.1% Uncommon | 41 pts |
| Bronze | Full House | Craft a Weapon with 2 Tools, Tips, and Attachments with all Circuit slots filled. | 30.2% Uncommon | 39 pts |
| Bronze | Together as One | Reassemble Rosetta. | 31.4% Uncommon | 38 pts |
| Bronze | EMT | Craft a Large Med Pack. | 31.6% Uncommon | 38 pts |
| Bronze | Hydra | Kill the Snowbeast. | 34.1% Uncommon | 36 pts |
| Silver | Intestinal Fortitude | Defeat the Hive Mind. | 35.6% Uncommon | 53 pts |
| Bronze | Snow Crash | Reach Tau Volantis. | 41.9% Common | 32 pts |
| Bronze | Critical Mass | Recover the shuttle. | 43.3% Common | 31 pts |
| Bronze | My Buddy | Retrieve Resources from a Scavenger Bot at a Bench. | 51.4% Common | 28 pts |
| Bronze | Overpowered Healing | Use quick heal to heal yourself 20 times. | 56.2% Common | 27 pts |
| Bronze | Circuit's Edge | Add a Circuit to a Weapon. | 58.7% Common | 26 pts |
| Bronze | Strapped | Craft a Weapon. | 63.9% Common | 25 pts |
| Bronze | Space Odyssey | Survive your first spacewalk. | 67.7% Common | 24 pts |
| Bronze | Stranger in a Strange Land | Complete the Prologue. | 86.3% Common | 21 pts |